Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873068 | 0.91 | MMP2 (0.42) | — | |
| SCHEMBL10372875 | 0.88 | GPR88 (0.39) | — | |
| SCHEMBL10543056 | 0.85 | ACACB (0.41) | ALOX5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3731770 | 0.84 | MAPT (0.43) | SMN1; SMN2 | |
| SCHEMBL10643650 | 0.83 | MAPT (0.37) | SMN1; SMN2 | |
| SCHEMBL10493405 | 0.82 | ATM (0.44) | SMN1; SMN2 | |
| SCHEMBL10639866 | 0.79 | FFAR1 (0.44) | ALOX5NPC1SMN1; SMN2 | |
| SCHEMBL10361855 | 0.79 | FAAH (0.49) | ALOX5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7828421 | 0.79 | ATM (0.42) | — | |
| SCHEMBL8597022 | 0.79 | ATM (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |