Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | DHFR | P00374 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | C1S | P09871 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103700 | 1.00 | ADRB1 (0.74) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL11096302 | 0.94 | KCNH2 (0.73) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL7924167 | 0.92 | KCNH2 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL8264176 | 0.91 | ADRB1 (0.69) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL12991 | 0.91 | ADRB1 (0.69) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL5043022 | 0.90 | ADRB1 (0.62) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL11211650 | 0.90 | ADRB1 (0.62) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL17281442 | 0.89 | ADRB1 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL3307690 | 0.89 | ADRB1 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27827352 | 0.89 | ADRB1 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-10-05 | — | — | US | disclosed |
| US-9675697-B2 | BET bromodomain inhibitors and therapeutic methods using the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-06-13 | — | — | US | disclosed |
| EP-0251011-B1 | INDOLYL PROPIONIC ACIDS | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4843091-A | Indolylpropionic acids, compositions of, and use thereof to inhibit thrombocyte aggregation | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | disclosed |
| EP-0251011-A1 | Indolyl propionic acids | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
| US-4477635-A | Polymeric triarylmethane dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | BRD4, BRDT, BRD3 | ADRB1 3674/4885KCNH2 4572/4885MAPT 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.