Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | DHFR | P00374 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | C1S | P09871 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373770 | 1.00 | ADRB1 (0.74) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL11096302 | 0.94 | KCNH2 (0.73) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL7924167 | 0.92 | KCNH2 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL8264176 | 0.91 | ADRB1 (0.69) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL12991 | 0.91 | ADRB1 (0.69) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL5043022 | 0.90 | ADRB1 (0.62) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL11211650 | 0.90 | ADRB1 (0.62) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL17281442 | 0.89 | ADRB1 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| SCHEMBL3307690 | 0.89 | ADRB1 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27827352 | 0.89 | ADRB1 (0.67) | ADRB1KCNH2MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031089-B1 | PROCESS FOR THE PRODUCTION OF N,N'-DIARYL-ALKYLENE DIAMINES OR N,N',N\"-TRIARYL-DIALKYLENE TRIAMINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-15 | — | — | EP | disclosed |
| EP-0031089-A1 | Process for the production of N,N'-diaryl-alkylene diamines or N,N',N\"-triaryl-dialkylene triamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-01 | — | — | EP | disclosed |