Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22416728 | 1.00 | KDM4E (0.48) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| SCHEMBL22790769 | 1.00 | KDM4E (0.48) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| SCHEMBL24728 | 1.00 | — | — | |
| SCHEMBL11573949 | 1.00 | KDM4E (0.48) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| SCHEMBL22316957 | 1.00 | KDM4E (0.48) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| SCHEMBL1485686 | 1.00 | KDM4E (0.48) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| SCHEMBL17041905 | 0.97 | KDM4E (0.46) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| Fluoride SCHEMBL9620604 | 0.97 | KDM4E (0.46) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| Ammonia Solution, Strong SCHEMBL28857856 | 0.97 | KDM4E (0.46) | KDM4EKCNH2ALDH1A1HSD17B10SHBG | |
| Bromide SCHEMBL28155616 | 0.97 | KDM4E (0.46) | KDM4EKCNH2ALDH1A1HSD17B10SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021218-A2 | PROCESS FOR THE PREPARATION OF 4-[3,5-BIS(2-HYDROXYPHENYL)-1H-1,2,4-TRIAZOL-1-YL]-BENZOIC ACID AND ITS AMINE SALTS | MSN LABORATORIES LIMITED (IN) | 2011-02-24 | — | — | WO | claimed |
| EP-1307458-B1 | PYRROLOTRIAZOLOPYRIMIDINONE DERIVATIVES | ALMIRALL LAB (ES) | 2007-10-03 | — | — | EP | claimed |
| US-7060824-B2 | Pyrrolotriazolopyrimidinone derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2006-06-13 | — | — | US | claimed |
| US-7034016-B2 | 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2006-04-25 | — | — | US | claimed |
| EP-1114021-B1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2004-07-14 | — | — | EP | claimed |
| US-20040019034-A1 | Pyrrolotriazolopyrimidinone derivatives | VIDAL JUAN BERNAT (ES) | 2004-01-29 | — | — | US | claimed |
| EP-1198464-B1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2003-10-08 | — | — | EP | claimed |
| US-20030120086-A1 | New salts of HMG-CoA reductase inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2003-06-26 | — | — | US | claimed |
| US-6583295-B1 | Amine salts of such as lovastatin, pravastatin, simvastatin, mevastatin or atorvastatin | LEK PHARMACEUTICALS D.D. (SI) | 2003-06-24 | — | — | US | claimed |
| EP-1307458-A1 | PYRROLOTRIAZOLOPYRIMIDINONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2003-05-07 | — | — | EP | claimed |
| US-20030060627-A1 | 8-Phenyl-6, 9-dihydro-[1,2,4] triazolo[3,4-i]purin-5-one derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2003-03-27 | — | — | US | claimed |
| EP-1198464-A1 | 8-PHENYL-6,9-DIHYDRO- 1,2,4]TRIAZOLO 3,4- i i /i ]PURIN-5-ONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2002-04-24 | — | — | EP | claimed |
| WO-2002012246-A1 | PYRROLOTRIAZOLOPYRIMIDINONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2002-02-14 | — | — | WO | claimed |
| EP-1114021-A1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2001-07-11 | — | — | EP | claimed |
| WO-2001007441-A1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2001-02-01 | — | — | WO | claimed |
| WO-2000017150-A1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | LEK PHARMACEUTICAL AND CHEMICAL COMPANY D.D. (DE) | 2000-03-30 | — | — | WO | claimed |
| EP-4107198-B1 | POLYISOCYANATE PREPARATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2024-03-13 | — | — | EP | disclosed |
| EP-3560975-B2 | IONICALLY HYDROPHILIZED POLYISOCYANATES AND ANTIOXIDANTS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-12-06 | — | — | EP | disclosed |
| EP-0065843-A1 | New M-4 and iso M-4 derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-12-01 | — | — | EP | disclosed |
| US-4003718-A | Substituted tetrahydropyrimidines | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060627-A1 | 8-Phenyl-6, 9-dihydro-[1,2,4] triazolo[3,4-i]purin-5-one derivatives | HYOU1, CHN2, PURB | KDM4E 4355/4885KCNH2 945/4885ALDH1A1 1064/4885 |
| US-20040019034-A1 | Pyrrolotriazolopyrimidinone derivatives | PDE5A, PDE3A, PDE2A | KDM4E 534/4885KCNH2 1730/4885ALDH1A1 966/4885 |
| US-20030120086-A1 | New salts of HMG-CoA reductase inhibitors | HMGCR, COASY, FDPS | KDM4E 2323/4885KCNH2 3023/4885ALDH1A1 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.