SCHEMBL103756

SCHEMBL103756

CCO[SiH](OCC)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ACHE P22303 2/20 0.38
ALDH1A1 P00352 2/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
ESR1 P03372 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
DHODH Q02127 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
TDP1 Q9NUW8 2/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL855225 0.90 TSHR (0.33) TSHRACHE
SCHEMBL2961096 0.86 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL23282492 0.83 TRPA1 (0.35) TSHRALDH1A1GAAMAPTHTT
SCHEMBL426600 0.83 ALDH1A1 (0.37) TSHRACHEALDH1A1GAAMAPT
SCHEMBL28688744 0.83 ALDH1A1 (0.50) TSHRALDH1A1GAAMAPTHTT
SCHEMBL27614186 0.83 TSHR (0.38) TSHRACHEALDH1A1GAAMAPT
SCHEMBL12119414 0.83 TSHR (0.38) TSHRACHEALDH1A1GAAMAPT
SCHEMBL4278109 0.80 TSHR (0.41) TSHRALDH1A1TDP1CYP3A4
SCHEMBL23282539 0.80 NPC1 (0.31) ALDH1A1GAAMAPTHTT
SCHEMBL28681778 0.79 TSHR (0.42) TSHRALDH1A1MAPTESR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE MEGA P&C ADVANCED MAT SHANGHAI CO LTD (CN) 2026-04-30 US claimed
CN-121574290-A Preparation method of ultra-high-toughness 4-methyl-1-pentene/alpha-olefin copolymer 万华化学集团股份有限公司 2026-02-27 CN claimed
EP-4653505-A1 COATING COMPOSITION, MATERIAL PRODUCT THEREOF, KIT, AND USE METHOD Mega P&C Advanced Materials (Shanghai) Co., Ltd. (CN) 2025-11-26 EP claimed
US-20250353967-A1 CURABLE SILOXANE RESIN COMPOSITION AND FILM INCLUDING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-20 US claimed
CN-120024900-A Nano silicon carbide microsphere and preparation method and application thereof 苏州纳微先进微球材料应用技术研究所有限公司 2025-05-23 CN claimed
CN-116478405-B Silane oligomer and preparation method and application thereof 万华化学集团股份有限公司 2025-05-13 CN claimed
CN-119751880-A Modified fluorosilicone polymer, two-component silicone sealant and preparation method thereof 广州白云科技股份有限公司 2025-04-04 CN claimed
CN-119752355-A Low-water-vapor-permeability organic silicon sealant and preparation method thereof 广州白云科技股份有限公司 2025-04-04 CN claimed
CN-119751877-A Modified fluorosilicone cross-linking agent, double-component silicone sealant and preparation method thereof 广州白云科技股份有限公司 2025-04-04 CN claimed
WO-2025055869-A1 COATING COMPOSITION, MATERIAL PRODUCT THEREOF, KIT, AND USE METHOD 麦加芯彩新材料科技(上海)股份有限公司 2025-03-20 WO claimed
EP-1209492-A1 Formation of materials such as waveguides with a refractive index step National University of Ireland Cork (IE) 2002-05-29 EP claimed
US-20010049427-A1 Room temperature curable silicone sealant MOMENTIVE PERFORMANCE MATERIALS INC. 2001-12-06 US claimed
EP-0660847-B1 HIGH TENSILE STRENGTH AMORPHOUS 1-BUTENE/PROPYLENE COPOLYMERS HUNTSMAN POLYMERS CORP (US) 2001-05-30 EP claimed
US-6111002-A Flame-retardant dispersion composition WACKER-CHEMIE GMBH (DE) 2000-08-29 US claimed
US-5858280-A Preparation of transparent methyl-modified silica gel YAMAMURA GLASS CO., LTD. (JP) 1999-01-12 US claimed
EP-0741760-B1 REDISPERSIBLE DISPERSION POWDER COMPOSITION, METHODS OF MANUFACTURING IT AND ITS USE WACKER CHEMIE GMBH (DE) 1997-11-19 EP claimed
EP-0457175-B1 Method of purification of alkoxysilanes TOSHIBA SILICONE (JP) 1997-02-12 EP claimed
EP-0484120-B1 Hydrogenpolysiloxanes and methods of making them SHINETSU CHEMICAL CO (JP) 1995-03-22 EP claimed
EP-0457175-A2 Method of purification of alkoxysilanes TOSHIBA SILICONE CO., LTD. (JP) 1991-11-21 EP claimed
US-4560711-A Transparent organopolysiloxane compositions TORAY SILICONE COMPANY, LTD. (JP) 1985-12-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE ILK, BMI1, C9 TSHR 4734/4885ACHE 1749/4885ALDH1A1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.