SCHEMBL426600

SCHEMBL426600

CCCO[SiH](OCCC)c1ccccc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.36
TSHR P16473 4/20 0.35
ACHE P22303 1/20 0.35
HPGD P15428 1/20 0.33
MAPK1 P28482 2/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TRPA1 O75762 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4278109 0.89 TSHR (0.41) ALDH1A1LMNATSHRMAPK1TDP1
SCHEMBL2961139 0.87 ALDH1A1 (0.42) ALDH1A1LMNATSHRHPGDMAPK1
SCHEMBL28681778 0.87 TSHR (0.42) ALDH1A1LMNATSHRMAPK1MEN1
SCHEMBL17391410 0.85 TSHR (0.44) ALDH1A1LMNATSHRMAPK1MEN1
SCHEMBL28693227 0.85 ALDH1A1 (0.46) ALDH1A1LMNAHPGDMAPK1KMT2A
SCHEMBL103756 0.83 TSHR (0.38) ALDH1A1TSHRACHETDP1CYP3A4
SCHEMBL11413682 0.82 MAPT (0.34) ALDH1A1TSHRACHETRPA1MAPT
SCHEMBL17391560 0.80 TSHR (0.38) ALDH1A1LMNATSHRMAPK1TDP1
SCHEMBL19809356 0.80 ALDH1A1 (0.37) ALDH1A1LMNATSHRHPGDMEN1
SCHEMBL17391547 0.79 CYP2D6 (0.43) LMNATSHRMAPK1CYP3A4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209492-B1 Formation of materials such as waveguides with a refractive index step NAT UNIV IRELAND CORK (IE) 2004-02-04 EP claimed
US-20020142096-A1 Induction gelation; optic diffraction; three-dimensional crosslinking CONNELL ANDREW (IE) 2002-10-03 US claimed
EP-1209492-A1 Formation of materials such as waveguides with a refractive index step National University of Ireland Cork (IE) 2002-05-29 EP claimed
US-20240270908-A1 POLYSILSESQUIOXANE COMPOSITION AND CURED PRODUCT NIPPON SHOKUBAI CO., LTD. (JP) 2024-08-15 US disclosed
WO-2022202800-A1 POLYSILSESQUIOXANE COMPOSITION AND CURED PRODUCT 株式会社日本触媒 2022-09-29 WO disclosed
CN-108250754-B Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2022-01-25 CN disclosed
EP-2540759-B1 Thermosetting resin composition and cured product of the same DAINIPPON INK & CHEMICALS (JP) 2014-08-06 EP disclosed
EP-2436734-B1 THERMOSETTING RESIN COMPOSITE AND CURED PRODUCT THEREOF DAINIPPON INK & CHEMICALS (JP) 2014-07-23 EP disclosed
EP-2671920-A1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT THEREOF, AND INTERLAYER ADHESIVE FILM FOR PRINTED WIRING BOARD DIC Corporation (JP) 2013-12-11 EP disclosed
US-20130309489-A1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT OF THE SAME, AND INTERLAMINAR ADHESIVE FILM USED FOR PRINTED WIRING BOARD DIC CORPORATION (JP) 2013-11-21 US disclosed
US-8470913-B2 Thermosetting resin composition and cured product of the same DIC CORPORATION (JP) 2013-06-25 US disclosed
EP-1659162-A1 HEAT-RESISTANT LABEL APPLICABLE AT HIGH TEMPERATURE Yushi-Seihin Co., Ltd. (JP) 2006-05-24 EP disclosed
US-20050070730-A1 Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-31 US disclosed
EP-0649126-B1 Label NOF CORP (JP) 1997-08-13 EP disclosed
EP-0431409-B1 A nonaqueous method for making silicone polymers GEN ELECTRIC (US) 1996-06-12 EP disclosed
US-5506016-A SILICONE RESIN AND INORGANIC MONOCRYSTALLINE FIBER; HEAT RESISTANCE NOF CORPORATION (JP) 1996-04-09 US disclosed
EP-0649126-A1 Label NOF CORPORATION (JP) 1995-04-19 EP disclosed
EP-0431409-A2 A nonaqueous method for making silicone polymers GENERAL ELECTRIC COMPANY (US) 1991-06-12 EP disclosed
US-4950779-A Nonaqueous method for making silicone oligomers GENERAL ELECTRIC COMPANY (US) 1990-08-21 US disclosed
US-4354013-A CHELATE COMPOUND CATALYST TOSHIBA SILICONE CO., LTD. (JP) 1982-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050070730-A1 Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes MLX, HAX1, GRIA3 ALDH1A1 2839/4885LMNA 3594/4885TSHR 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.