Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875856 | 0.80 | TP53 (0.46) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL8032579 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL19795961 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL19041177 | 0.76 | CES2 (0.49) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL31116625 | 0.76 | TSHR (0.48) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL305842 | 0.76 | TSHR (0.48) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL19795897 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL5773977 | 0.75 | NPSR1 (0.41) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL5779893 | 0.74 | NPSR1 (0.44) | ALDH1A1TSHRGLAKMT2ATP53 | |
| SCHEMBL19041264 | 0.74 | TSHR (0.43) | ALDH1A1TSHRGLAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |