Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773977 | 0.78 | NPSR1 (0.41) | NPSR1TP53ALDH1A1HTTNPC1 | |
| SCHEMBL5094475 | 0.74 | MEN1 (0.60) | NPSR1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL5699186 | 0.74 | HTT (0.40) | NPSR1TP53TRPM8ALDH1A1HTT | |
| SCHEMBL5765975 | 0.74 | NPSR1 (0.38) | NPSR1TP53TRPM8ALDH1A1HTT | |
| SCHEMBL2511509 | 0.74 | NPSR1 (0.38) | NPSR1TP53TRPM8ALDH1A1RAB9A | |
| SCHEMBL10375754 | 0.74 | ALDH1A1 (0.48) | NPSR1TP53ALDH1A1HTTNPC1 | |
| SCHEMBL4559026 | 0.71 | MEN1 (0.40) | NPSR1ALDH1A1HTTKMT2AGLA | |
| SCHEMBL19041278 | 0.71 | CES2 (0.48) | NPSR1ALDH1A1RAB9AKMT2ATSHR | |
| SCHEMBL3966094 | 0.70 | ALDH1A1 (0.41) | NPSR1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL19795974 | 0.70 | CES2 (0.45) | NPSR1ALDH1A1HTTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513833-B1 | NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1513833-A1 | NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000834-A1 | NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2003-12-31 | — | — | WO | disclosed |