Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447510 | 0.73 | KDM4E (0.61) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL11161014 | 0.71 | KDM4E (0.59) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10821596 | 0.69 | PDXK (0.38) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4466115 | 0.67 | KDM4E (0.58) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11581910 | 0.63 | PRKCG (0.39) | PRKCGPRKCAPRKCD | |
| SCHEMBL4865054 | 0.61 | LMNA (0.38) | KDM4E | |
| SCHEMBL22019794 | 0.60 | KDM4E (0.36) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4459404 | 0.58 | KMT2A (0.51) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18149361 | 0.57 | PRKCG (0.36) | KDM4EPRKCGPRKCAPRKCD | |
| SCHEMBL2044812 | 0.57 | PRKCG (0.36) | KDM4ECYP1A2PRKCGPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168288-B1 | Aminomethyl-6-furo-[3,4-c]pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1990-04-25 | — | — | EP | claimed |
| US-4602020-A | ANTIALLERGENS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1986-07-22 | — | — | US | claimed |
| JP-61068490-A | — | — | None | — | — | JP | disclosed |
| US-4602020-A | ANTIALLERGENS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1986-07-22 | — | — | US | disclosed |
| US-4602020-A | ANTIALLERGENS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1986-07-22 | — | — | US | disclosed |
| JP-S6168490-A | 1,3-DIHYDRO-6-AMINOMETHYL-7-HYDROXY-FURO-(3,4-C)-PYRIDINE DERIVATIVE, MANUFACTURE AND MEDICINAL COMPOSITION | SCRAS | 1986-04-08 | — | — | JP | disclosed |