Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11161014 | 0.98 | KDM4E (0.59) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL4466115 | 0.93 | KDM4E (0.58) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL4459404 | 0.79 | KMT2A (0.51) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL22019794 | 0.74 | KDM4E (0.36) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL10376243 | 0.73 | KDM4E (0.36) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL10821596 | 0.73 | PDXK (0.38) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL23857473 | 0.70 | PDE4D (0.40) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL12673717 | 0.69 | KMT2A (0.39) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL10732292 | 0.69 | KDM4E (0.42) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL13107698 | 0.69 | KDM4E (0.42) | KDM4EKMT2AMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028470-A1 | Detection and Treatment of Schizophrenia | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2011-02-03 | — | — | US | claimed |
| US-7645882-B2 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2010-01-12 | — | — | US | claimed |
| US-20070123577-A1 | Inhibitor of protein modification products formation | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2007-05-31 | — | — | US | claimed |
| EP-1693369-A1 | PROTEIN MODIFIER PRODUCTION INHIBITOR | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2006-08-23 | — | — | EP | claimed |
| EP-1398316-B1 | Process for the preparation of 1,3-Dihydro-6-methylfuro(3,4-c)pyridin-7-ol Derivatives | GENERICS UK LTD (GB) | 2006-06-14 | — | — | EP | claimed |
| WO-2005090356-A1 | 1,3 DIHYDROFURO [3,4-c]PYRIDINES AND THEIR PREPARATION | DSM IP ASSETS B.V. (NL) | 2005-09-29 | — | — | WO | claimed |
| EP-1398316-A2 | Process for the preparation of 1,3-Dihydro-6-methylfuro(3,4-c)pyridin-7-ol Derivatives | Generics (UK) Limited (GB) | 2004-03-17 | — | — | EP | claimed |
| US-4735950-A | DIURETICS, HYPOTENSIVE AGENT, ANTILIPEMIC AGENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) | 1988-04-05 | — | — | US | claimed |
| US-4585776-A | DIURETIC HYPOTENSIVE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1986-04-29 | — | — | US | claimed |
| US-4581363-A | DIURETICS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1986-04-08 | — | — | US | claimed |
| EP-0035716-B1 | 4-ALPHA-CYCLOAMINOARYLMETHYL-6-METHYL-1,3-DIHYDRO FURO (3,4-C)PYRIDIN-7-OLS, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1983-06-29 | — | — | EP | claimed |
| US-4383998-A | Furo-(3,4-c)-pyridine derivatives and their pharmaceutical use | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1983-05-17 | — | — | US | claimed |
| EP-0035716-A1 | 4-Alpha-cycloaminoarylmethyl-6-methyl-1,3-dihydro furo (3,4-c)pyridin-7-ols, their preparation and use | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | claimed |
| US-20140335517-A1 | DETECTION AND TREATMENT OF SCHIZOPHRENIA | RENASCIENCE CO LTD (JP) | 2014-11-13 | — | — | US | disclosed |
| US-8809329-B2 | Detection and treatment of schizophrenia | TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) | 2014-08-19 | — | — | US | disclosed |
| EP-2662453-A2 | Detection and treatment of schizophrenia | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-4383998-A | Furo-(3,4-c)-pyridine derivatives and their pharmaceutical use | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1983-05-17 | — | — | US | disclosed |
| US-4383998-A | Furo-(3,4-c)-pyridine derivatives and their pharmaceutical use | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1983-05-17 | — | — | US | disclosed |
| US-4335241-A | INTERMEDIATES FOR ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0035716-A1 | 4-Alpha-cycloaminoarylmethyl-6-methyl-1,3-dihydro furo (3,4-c)pyridin-7-ols, their preparation and use | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123577-A1 | Inhibitor of protein modification products formation | SERPINB6, PROC, PLPBP | KDM4E 2177/4885KMT2A 2334/4885MEN1 1277/4885 |
| US-20110028470-A1 | Detection and Treatment of Schizophrenia | GLO1, CBR1, AOX1 | KDM4E 1357/4885KMT2A 1703/4885MEN1 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.