Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20703686 | 0.81 | ALOX12 (0.43) | TSHRALDH1A1LMNAGAA | |
| SCHEMBL3592110 | 0.74 | ALDH1A1 (0.34) | HTTTSHRPIK3CDPIK3R1MTOR | |
| SCHEMBL30991588 | 0.74 | PDE3B (0.51) | HTTTSHRLMNANPC1RAB9A | |
| SCHEMBL653919 | 0.74 | PDE3B (0.51) | HTTTSHRLMNANPC1RAB9A | |
| SCHEMBL10164948 | 0.73 | PIK3CG (0.40) | HTTTSHRPIK3CDPIK3R1MTOR | |
| SCHEMBL10376218 | 0.73 | HTT (0.44) | HTTTSHRPLK1ALDH1A1ATAD2 | |
| SCHEMBL17076653 | 0.71 | ATAD2 (0.52) | HTTTSHRPLK1ALDH1A1ATAD2 | |
| SCHEMBL8879021 | 0.69 | HTT (0.54) | HTTTSHRPLK1ALDH1A1THRB | |
| SCHEMBL13140225 | 0.68 | KMO (0.51) | HTTTSHRPIK3CDPIK3R1MTOR | |
| SCHEMBL17807815 | 0.68 | PIK3CD (0.41) | HTTTSHRPIK3CDPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263299-B1 | BENZOXAZINES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4804394-A | Benzoxazines and use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0263299-A1 | Benzoxazines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-04-13 | — | — | EP | disclosed |