Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.41 |
| ▸ | NRP1 | O14786 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785514 | 0.90 | EPHA2 (0.46) | CXCR4EPHA2OPRM1 | |
| SCHEMBL8969918 | 0.88 | EPHA2 (0.49) | CXCR4EPHA2OPRM1NTSR2NTSR1 | |
| SCHEMBL10378224 | 0.87 | EPHA2 (0.48) | EPHA2NTSR2NTSR1SORT1XIAP | |
| SCHEMBL10378950 | 0.87 | EPHA2 (0.48) | CXCR4EPHA2OPRM1NTSR2NTSR1 | |
| SCHEMBL7785522 | 0.87 | OPRM1 (0.43) | CXCR4EPHA2OPRM1NTSR2NTSR1 | |
| SCHEMBL31303183 | 0.86 | NRP1 (0.52) | CXCR4EPHA2OPRM1NTSR2NTSR1 | |
| SCHEMBL7785535 | 0.86 | NTSR2 (0.42) | EPHA2OPRM1NTSR2NTSR1SORT1 | |
| SCHEMBL8970642 | 0.86 | EPHA2 (0.47) | EPHA2NTSR2NTSR1SORT1NRP1 | |
| SCHEMBL7780971 | 0.86 | EPHA2 (0.47) | CXCR4EPHA2 | |
| SCHEMBL9508406 | 0.84 | EPHA2 (0.41) | CXCR4EPHA2OPRM1NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | disclosed |