Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380958 | 0.88 | PLA2G2A (0.59) | ADAM17LMNAALDH1A1ICMTHTR6 | |
| SCHEMBL9584665 | 0.87 | POLB (0.54) | LMNAALDH1A1POLBHDAC1HDAC8 | |
| SCHEMBL9583439 | 0.87 | POLB (0.54) | LMNAALDH1A1POLBHDAC1HDAC8 | |
| SCHEMBL9583565 | 0.87 | POLB (0.54) | LMNAALDH1A1POLBHDAC1HDAC8 | |
| SCHEMBL9584383 | 0.82 | USP2 (0.50) | ADAM17LMNAALDH1A1ICMTPOLB | |
| Hydrochloric Acid SCHEMBL9584104 | 0.82 | USP2 (0.49) | ADAM17LMNAALDH1A1ICMTPOLB | |
| SCHEMBL9585826 | 0.81 | ICMT (0.53) | ADAM17LMNAALDH1A1ICMTSMN1; SMN2 | |
| SCHEMBL9584364 | 0.81 | ADAM17 (0.58) | ADAM17LMNAALDH1A1ICMTPOLB | |
| Water SCHEMBL10380911 | 0.80 | ADAM17 (0.57) | ADAM17LMNAALDH1A1ICMTPOLB | |
| Water SCHEMBL10380909 | 0.80 | ADAM17 (0.57) | ADAM17LMNAALDH1A1ICMTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990005721-A1 | ALPHA-AMINO-INDOLE-3-ACETIC ACIDS USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1990-05-31 | — | — | WO | claimed |