SCHEMBL1038249

SCHEMBL1038249

CCCCCOC(=O)CP(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 1/20 0.43
ITGA4 P13612 1/20 0.43
ESR1 P03372 3/20 0.42
NAAA Q02083 1/20 0.41
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
THRB P10828 2/20 0.40
THRA P10827 1/20 0.40
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1036203 0.99 NAAA (0.44) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL1035930 0.99 NAAA (0.44) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL1036933 0.99 NAAA (0.44) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL1035836 0.99 NAAA (0.44) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL2882497 0.99 NAAA (0.44) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL1038238 0.91 ITGB1 (0.40) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL1035772 0.90 ALDH1A1 (0.37) ITGB1ITGA4THRBTHRATSHR
SCHEMBL1038734 0.89 FAAH (0.47) ITGB1ITGA4ESR1NAAACNR1
SCHEMBL1039014 0.86 NLRP3 (0.44) TSHRCYP3A4MAPK1MEN1KMT2A
SCHEMBL1037305 0.84 TDP1 (0.38) ITGB1ITGA4ESR1THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1814891-B1 BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES BASF SE (DE) 2011-01-26 EP disclosed