Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 11/20 | 1.00 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.70 |
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | PLAT | P00750 | 1/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.57 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.53 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826365 | 0.84 | ALOX15 (1.00) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL10386151 | 0.83 | ALOX15 (0.71) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL9826900 | 0.82 | ALOX15 (1.00) | ALOX15 | |
| SCHEMBL9826824 | 0.81 | ALOX15 (0.75) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL24438367 | 0.80 | TMPRSS4 (0.76) | ALOX15KLKB1P2RX1P2RX4P2RX7 | |
| SCHEMBL7172686 | 0.77 | TMPRSS4 (0.77) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL330564 | 0.75 | P2RX1 (0.76) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL25348257 | 0.75 | KLKB1 (0.64) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL18290067 | 0.75 | PNLIP (0.67) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL27772533 | 0.74 | ALOX15 (0.85) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939133-A | N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade | WARNER-LAMBERT COMPANY (US) | 1990-07-03 | — | — | US | disclosed |