Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PNLIP | P16233 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827104 | 0.87 | ALOX15 (0.72) | ALOX15KLKB1CNR1ALDH1A1PLAU | |
| SCHEMBL9826705 | 0.85 | ALOX15 (0.69) | ALOX15KLKB1TP53ALDH1A1LMNA | |
| SCHEMBL10384347 | 0.83 | ALOX15 (1.00) | ALOX15KLKB1PLAUF2F10 | |
| SCHEMBL9826852 | 0.82 | CNR1 (0.56) | ALOX15CNR1TP53ALDH1A1LMNA | |
| SCHEMBL24438365 | 0.80 | ALDH1A1 (0.69) | TP53ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30692666 | 0.80 | ALDH1A1 (0.69) | TP53ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13189704 | 0.77 | P2RX1 (0.67) | TP53ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11480131 | 0.77 | ALDH1A1 (0.67) | TP53ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10412160 | 0.77 | CNR1 (0.50) | ALOX15CNR1TP53ALDH1A1LMNA | |
| SCHEMBL9827298 | 0.76 | KLKB1 (0.62) | ALOX15KLKB1ALDH1A1PLGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939133-A | N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade | WARNER-LAMBERT COMPANY (US) | 1990-07-03 | — | — | US | disclosed |