Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950404 | 0.92 | REN (0.45) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL1037868 | 0.90 | REN (0.41) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4583128 | 0.89 | REN (0.41) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4593222 | 0.87 | REN (0.43) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4593223 | 0.87 | REN (0.43) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4593225 | 0.87 | REN (0.43) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4583827 | 0.86 | REN (0.43) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4583818 | 0.86 | REN (0.43) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4582103 | 0.85 | REN (0.41) | RENCYP3A4MTNR1AMTNR1B | |
| SCHEMBL4582108 | 0.85 | REN (0.41) | RENCYP3A4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |
| US-20090325947-A1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2009-12-31 | — | — | US | disclosed |
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325947-A1 | NITRATE ESTERS OF PIPERIDINES | NOS2, NOS1, NOS3 | REN 29/4885CYP3A4 674/4885MTNR1A 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.