Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.47 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564606 | 0.85 | ALDH1A1 (0.45) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10384497 | 0.81 | NPC1 (0.51) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL4054163 | 0.81 | NPC1 (0.47) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10384501 | 0.77 | RAB9A (0.44) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10385317 | 0.74 | NPC1 (0.45) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL9016292 | 0.74 | TAS1R3 (0.43) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL21778995 | 0.74 | NPC1 (0.41) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL593507 | 0.74 | NPC1 (0.54) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL14127183 | 0.74 | NPC1 (0.54) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL11706963 | 0.73 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EHKDC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946585-A | USING MERCAPTOBENZOTHIAZOLE | AMERICAN CYANAMID COMPANY (US) | 1990-08-07 | — | — | US | disclosed |