Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | SMAD2 | Q15796 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054023 | 0.85 | ALDH1A1 (0.45) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10384497 | 0.81 | NPC1 (0.51) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10384499 | 0.81 | NPC1 (0.47) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10384501 | 0.80 | RAB9A (0.44) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL25488551 | 0.79 | DYRK1A (0.34) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL9016292 | 0.78 | TAS1R3 (0.43) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL11706963 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL21778995 | 0.74 | NPC1 (0.41) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL10385317 | 0.74 | NPC1 (0.45) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL4641057 | 0.74 | TYMS (0.43) | KDM4EALDH1A1HSD17B10DYRK1ACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584748-B2 | Spirocyclic compounds | C4 THERAPEUTICS, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210292285-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | NUVATION BIO INC (US) | 2021-09-23 | — | — | US | disclosed |
| US-20210032245-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2021-02-04 | — | — | US | disclosed |
| WO-2020041562-A1 | SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT | CLAVIUS PHARMACEUTICALS, LLC (US) | 2020-02-27 | — | — | WO | disclosed |
| EP-3524244-A1 | BENZOTHIAZOLE COMPOUNDS AS SUMO ACTIVATORS | Icahn School of Medicine at Mount Sinai (US) | 2019-08-14 | — | — | EP | disclosed |
| US-7598026-B2 | Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJIFILM CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |
| CN-101124516-A | Pattern forming material, pattern forming apparatus, and pattern forming method | FUJI FILM CORP (JP) | 2008-02-13 | — | — | CN | disclosed |
| US-20070172777-A1 | Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2007-07-26 | — | — | US | disclosed |
| US-20050170299-A1 | Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2005-08-04 | — | — | US | disclosed |
| US-6916601-B2 | Image-forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| EP-0222970-A1 | Sulphoalkylation process | Agfa-Gevaert AG (DE) | 1987-05-27 | — | — | EP | disclosed |
| US-4539408-A | Process for the preparation of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-09-03 | — | — | US | disclosed |
| US-4504668-A | Process for the preparation of N-sulfoalkyl quaternary salts of nitrogen heterocyclics | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-03-12 | — | — | US | disclosed |
| EP-0064667-B1 | PROCESS FOR THE PREPARATION OF SULFOALKYL QUATERNARY SALTS | Agfa-Gevaert AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0055428-B1 | BIS-(3-SULFOPROPYL)ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ALKYLATING AGENTS FOR ORGANIC BASES | Agfa-Gevaert AG (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0034279-B1 | SULFOALKYLATING AGENTS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE MANUFACTURE OF QUANTERNARY SULFOALKYL SALTS | Agfa-Gevaert AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0064667-A1 | Process for the preparation of sulfoalkyl quaternary salts | Agfa-Gevaert AG (DE) | 1982-11-17 | — | — | EP | disclosed |
| EP-0055428-A1 | Bis-(3-sulfopropyl)ethers, process for their preparation and their use as alkylating agents for organic bases | Agfa-Gevaert AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4308390-A | Process for the production of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1981-12-29 | — | — | US | disclosed |
| EP-0034279-A2 | Sulfoalkylating agents, process for their preparation and their use in the manufacture of quanternary sulfoalkyl salts | Agfa-Gevaert AG (DE) | 1981-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292285-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | ADORA2A, ADORA3, ADORA1 | NPC1 4008/4885RAB9A 2816/4885KDM4E 4200/4885 |
| US-20210032245-A1 | SPIROCYCLIC COMPOUNDS | CRBN, RBX1, XIAP | NPC1 2125/4885RAB9A 3313/4885KDM4E 1861/4885 |
| US-11584748-B2 | Spirocyclic compounds | CRBN, RBX1, XIAP | NPC1 2125/4885RAB9A 3313/4885KDM4E 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.