SCHEMBL10384841

SCHEMBL10384841

O=[N+]([O-])c1cc(S(=O)(=O)O)ccc1S(=O)(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF18A Q8NI77 1/20 0.68
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.56
HPGD P15428 3/20 0.50
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 5/20 0.47
HTT P42858 4/20 0.47
LMNA P02545 3/20 0.47
MAPT P10636 2/20 0.47
PKM P14618 1/20 0.47
NOD2 Q9HC29 2/20 0.47
RAB9A P51151 1/20 0.47
NSD2 O96028 1/20 0.46
GAA P10253 1/20 0.46
PLCG1 P19174 1/20 0.46
DNMT1 P26358 1/20 0.46
CASP6 P55212 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742841 0.86 L3MBTL1 (0.53) KIF18AKMT2AMEN1HPGDALDH1A1
SCHEMBL11442799 0.86 KIF18A (0.51) KIF18AKMT2AMEN1HPGDALDH1A1
SCHEMBL3201792 0.83 ALDH1A1 (0.58) KIF18AKMT2AMEN1HPGDALDH1A1
SCHEMBL9644188 0.81 KIF18A (0.68) KIF18AKMT2AMEN1ALDH1A1TDP1
SCHEMBL29355257 0.81 KIF18A (1.00) KIF18AKMT2AMEN1HPGDALDH1A1
SCHEMBL6744096 0.81 KIF18A (0.68) KIF18AKMT2AMEN1ALDH1A1TDP1
SCHEMBL15307422 0.81 KIF18A (0.68) KIF18AKMT2AMEN1ALDH1A1TDP1
SCHEMBL10040107 0.81 KIF18A (0.68) KIF18AKMT2AMEN1HPGDALDH1A1
SCHEMBL11727447 0.81 KIF18A (1.00) KIF18AKMT2AMEN1HPGDALDH1A1
SCHEMBL2041279 0.80 KMT2A (1.00) KIF18AKMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4906740-A Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed