Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385217 | 0.70 | LMNA (0.62) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| SCHEMBL10385167 | 0.70 | LMNA (0.62) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| SCHEMBL10385165 | 0.70 | LMNA (0.62) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| SCHEMBL10384658 | 0.69 | CHRM5 (0.44) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| Phosphoric Acid SCHEMBL10385164 | 0.66 | LMNA (0.56) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| Phosphoric Acid SCHEMBL10384531 | 0.66 | LMNA (0.56) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| Pilocarpine SCHEMBL41890 | 0.66 | LMNA (1.00) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| Pilocarpine SCHEMBL678045 | 0.66 | LMNA (1.00) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| Pilocarpine SCHEMBL3078492 | 0.66 | LMNA (1.00) | CHRM5LMNACYP3A4CHRM4CHRM1 | |
| Pilocarpine SCHEMBL725541 | 0.65 | LMNA (1.00) | CHRM5LMNACYP3A4CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977176-A | Pilocarpine compounds which are used as pharmaceutical agents | SANDOZ LTD. (CH) | 1990-12-11 | — | — | US | claimed |
| US-4835174-A | Pilocarpine derivatives | SANDOZ LTD. (CH) | 1989-05-30 | — | — | US | claimed |
| US-4977176-A | Pilocarpine compounds which are used as pharmaceutical agents | SANDOZ LTD. (CH) | 1990-12-11 | — | — | US | disclosed |
| US-4835174-A | Pilocarpine derivatives | SANDOZ LTD. (CH) | 1989-05-30 | — | — | US | disclosed |