Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849844 | 0.79 | CYP19A1 (0.37) | HTTHSD17B10KDM4ECYP19A1ALDH1A1 | |
| SCHEMBL12815928 | 0.78 | MAPT (0.35) | ADRA2AADORA2AHTTHSD17B10ALDH1A1 | |
| SCHEMBL8481612 | 0.78 | MAPT (0.35) | ADRA2AADORA2AHTTHSD17B10KDM4E | |
| SCHEMBL3843112 | 0.74 | CYP19A1 (0.39) | HTTHSD17B10CYP19A1ALDH1A1MAPT | |
| SCHEMBL7533650 | 0.71 | MAPT (0.35) | ADRA2AADORA2AHTTHSD17B10ALDH1A1 | |
| SCHEMBL12815787 | 0.69 | MAPT (0.36) | HTTALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3845811 | 0.68 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL1629378 | 0.66 | MAPT (0.37) | ADRA2AADORA2AHTTHSD17B10ALDH1A1 | |
| SCHEMBL6224936 | 0.66 | MAPT (0.36) | ADRA2AADORA2AHTTHSD17B10KDM4E | |
| SCHEMBL8480278 | 0.66 | ACHE (0.38) | HTTKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923997-A | CURABLE | LOCTITE CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4806608-A | Curable siloxane maleimide composition | LOCTITE CORPORATION (US) | 1989-02-21 | — | — | US | disclosed |