SCHEMBL3849844

SCHEMBL3849844

C#Cc1c(-c2ccccc2)[c]c(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.37
PTPN1 P18031 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843112 0.88 CYP19A1 (0.39) CYP19A1ALDH1A1ALOX15HSD17B10MAPT
SCHEMBL10385262 0.79 ADRA2A (0.39) CYP19A1ALDH1A1HSD17B10MAPTHTT
SCHEMBL619469 0.79 MAPT (0.43) ALDH1A1HSD17B10MAPTLMNAHTT
SCHEMBL21248657 0.76 ALDH1A1 (0.46) PTPN1ALDH1A1ALOX15HSD17B10MAPT
SCHEMBL28769194 0.74 CYP19A1 (0.48) CYP19A1PTPN1ALDH1A1ALOX15HSD17B10
SCHEMBL3845811 0.73 CYP19A1 (0.34) CYP19A1
SCHEMBL3845011 0.69 ADORA1 (0.35) CYP19A1ALDH1A1ALOX15HSD17B10MAPT
SCHEMBL3846385 0.69
SCHEMBL3840723 0.69 CYP19A1 (0.34) CYP19A1
SCHEMBL21248606 0.69 MAPT (0.39) PTPN1ALDH1A1HSD17B10MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed