SCHEMBL194732

SCHEMBL194732

CC(C)(O)C(=O)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.52
CES1 P23141 3/20 0.52
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
POLB P06746 1/20 0.50
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ELANE P08246 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GSK3B P49841 2/20 0.45
SRD5A2 P31213 1/20 0.45
MAPK1 P28482 1/20 0.45
PPARA Q07869 2/20 0.44
FABP2 P12104 1/20 0.44
PPARG P37231 1/20 0.44
SLC22A12 Q96S37 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10940129 0.94 CES2 (0.64) CES2CES1ALOX15TSHRPOLB
SCHEMBL10943769 0.94 MAPK1 (0.55) CES2CES1ALOX15TSHRPOLB
SCHEMBL11298330 0.88 CA2 (0.46) CES2CES1TSHRCA2ELANE
SCHEMBL198250 0.84 CES2 (0.54) CES2CES1ALOX15TSHRPOLB
SCHEMBL17187854 0.84 CES2 (0.54) CES2CES1ALOX15TSHRPOLB
SCHEMBL9329708 0.82 ALDH1A1 (0.42) CES2CES1TSHRPOLBCA2
SCHEMBL10887646 0.82 CES2 (0.52) CES2CES1ALOX15TSHRPOLB
SCHEMBL3443593 0.82 CES2 (0.52) CES2CES1ALOX15TSHRPOLB
SCHEMBL15251658 0.81 RXRA (0.44) CA1CA2NPC1RAB9ASMN1; SMN2
SCHEMBL4419639 0.81 ALDH1A1 (0.50) CA2ELANESRD5A2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4717605-A PHOTOPOLYMERIZING POLYEPOXIDE SYSTEMS, UNSATURATED COMPONENTS, FREE RADICAL INITIATORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-05 US claimed
EP-0107198-B1 USE OF 2-HYDROXY-2-METHYL-(P-CHLOROPROPIONPHENONE) AS A PHOTOINITIATOR CIBA-GEIGY AG (CH) 1987-07-08 EP claimed
EP-0107198-A1 Use of 2-hydroxy-2-methyl-(p-chloropropionphenone) as a photoinitiator CIBA-GEIGY AG (CH) 1984-05-02 EP claimed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US claimed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP claimed
JP-1308404-A None JP disclosed
US-20240317942-A1 THIOL-CONTAINING COMPOSITION, PHOTOSETTING COMPOSITION, AND THERMOSETTING COMPOSITION RESONAC CORPORATION (JP) 2024-09-26 US disclosed
EP-4375302-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION Resonac Corporation (JP) 2024-05-29 EP disclosed
CN-117651722-A Thiol-containing composition, photocurable composition, and thermosetting composition 株式会社力森诺科 2024-03-05 CN disclosed
CN-117466726-A Preparation method of 4-hydroxy phenyl ketone compound 天津久日新材料股份有限公司 2024-01-30 CN disclosed
WO-2023003011-A1 THIOL-CONTAINING COMPOSITION, PHOTOCURABLE COMPOSITION, AND THERMOSETTING COMPOSITION 昭和電工株式会社 2023-01-26 WO disclosed
CN-104641295-B Photosensitive resin composition for photospacer and photospacer 株式会社日本触媒 2020-03-03 CN disclosed
US-4347111-A PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS, HARDENING OF PRINTING DYES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-08-31 US disclosed
EP-0007468-B1 COMPOSITIONS PHOTODURCISSABLES CIBA-GEIGY AG (CH) 1982-04-07 EP disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed
US-4284485-A STABILIZED WITH A POLYALKYLPIPERIDINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
EP-0007468-A1 Compositions photodurcissables CIBA-GEIGY AG (CH) 1980-02-06 EP disclosed