Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | PI4KA | P42356 | 2/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387490 | 0.98 | TLR7 (0.44) | TLR7CYP1A2CYP2D6MAPK1POLB | |
| SCHEMBL11033550 | 0.73 | ADORA2A (0.45) | TLR7CYP1A2CYP2D6MAPK1TSHR | |
| SCHEMBL11269779 | 0.72 | ADORA2A (0.66) | CYP1A2CYP2D6MAPK1TSHRADORA2A | |
| SCHEMBL10387483 | 0.70 | ADORA2A (0.45) | TLR7CYP1A2CYP2D6MAPK1TSHR | |
| SCHEMBL12843984 | 0.70 | TLR7 (0.55) | TLR7CYP1A2CYP2D6MAPK1POLB | |
| SCHEMBL1082007 | 0.69 | ADORA2A (0.61) | TLR7CYP1A2CYP2D6MAPK1ALDH1A1 | |
| SCHEMBL12775415 | 0.67 | TLR7 (0.52) | TLR7CYP1A2CYP2D6MAPK1POLB | |
| SCHEMBL22084384 | 0.67 | DAPK1 (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8921749 | 0.66 | ADORA1 (0.40) | MAPK1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL22084385 | 0.66 | PDE10A (0.46) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975433-A | DRUG DELIVERY FOR TREATING SKIN DISORDERS | UNIVERSITY OF FLORIDA (US) | 1990-12-04 | — | — | US | disclosed |
| US-4845081-A | PRODRUGS, URACILS | UNIVERSITY OF FLORIDA (US) | 1989-07-04 | — | — | US | disclosed |