Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923800 | 0.84 | ADORA2A (0.56) | ADORA1MAPK1ADORA2AADAAHCY | |
| SCHEMBL8921694 | 0.81 | CYP1A2 (0.51) | ADORA1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL18410857 | 0.81 | MAPK1 (0.57) | ADORA1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL8922846 | 0.74 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL11269779 | 0.72 | ADORA2A (0.66) | ADORA1MAPK1ADORA2AAHCY | |
| SCHEMBL11033550 | 0.70 | ADORA2A (0.45) | ADORA1MAPK1ADORA2AAHCY | |
| SCHEMBL8617303 | 0.70 | EGFR (0.47) | ADORA1MAPK1ADORA2AAHCY | |
| SCHEMBL8617308 | 0.70 | EGFR (0.47) | ADORA1MAPK1ADORA2AAHCY | |
| SCHEMBL8922569 | 0.69 | TK1 (0.57) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL2116000 | 0.69 | ADORA2A (0.64) | ADORA1MAPK1ADORA2AAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |