Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1301323 | 0.93 | HRH3 (0.49) | HRH3SLC29A1SMN1; SMN2MEN1LMNA | |
| Hydrochloric Acid SCHEMBL1950623 | 0.92 | HRH3 (0.48) | HRH3SLC29A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL8560879 | 0.86 | KDM4E (0.51) | HRH3SMN1; SMN2MEN1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL3107158 | 0.85 | PAOX (0.53) | HRH3SLC29A1MEN1KMT2ADRD3 | |
| SCHEMBL8562390 | 0.84 | CYP2D6 (0.54) | HRH3SMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL10387010 | 0.83 | ALDH1A1 (0.49) | HRH3SLC29A1MEN1KMT2ATSHR | |
| SCHEMBL8568373 | 0.80 | HRH3 (0.52) | HRH3SMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL29085663 | 0.78 | PAOX (0.49) | HRH3SLC29A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL16845085 | 0.78 | HRH3 (0.50) | HRH3SLC29A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL11025698 | 0.77 | HRH3 (0.47) | HRH3SLC29A1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958024-A | REACTION OF CARBAMATE SUBSTITUTED ACRYLIC ESTER, VASODILATORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4914227-A | FOR VASODILATING AND HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4739106-A | VASODILATION, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | disclosed |