Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388554 | 0.98 | CCR3 (0.71) | CCR3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL8984830 | 0.87 | SLC6A3 (0.61) | CCR3SIGMAR1MEN1KMT2A | |
| SCHEMBL8092982 | 0.87 | SIGMAR1 (0.85) | CCR3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL3031390 | 0.84 | SIGMAR1 (0.66) | CCR3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL5544570 | 0.84 | SIGMAR1 (0.66) | CCR3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL8091647 | 0.83 | CCR3 (0.96) | CCR3SIGMAR1KMT2A | |
| SCHEMBL3034316 | 0.83 | SIGMAR1 (0.66) | CCR3SIGMAR1MEN1TP53CYP1A2 | |
| SCHEMBL8092895 | 0.82 | CCR3 (1.00) | CCR3SIGMAR1KMT2A | |
| SCHEMBL30671729 | 0.80 | SIGMAR1 (0.96) | CCR3SIGMAR1 | |
| SCHEMBL7366514 | 0.80 | SIGMAR1 (1.00) | CCR3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971957-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS, BENZENECARBOXAMIDOPHOSPHONATES OR BENZENETHIOCARBOXAMIDOPHOSPHONATES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1990-11-20 | — | — | US | disclosed |