Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675676 | 0.82 | KMT2A (0.49) | DRD4SLC6A2CCKAROPRM1DRD3 | |
| SCHEMBL17342578 | 0.81 | LMNA (0.68) | DRD4SLC6A2CCKAROPRM1DRD3 | |
| SCHEMBL696889 | 0.80 | HPGD (0.47) | LMNACYP1A2CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL28568899 | 0.79 | KLK7 (0.54) | DRD4SLC6A2CCKAROPRM1DRD3 | |
| SCHEMBL28571893 | 0.79 | KLK7 (0.54) | DRD4SLC6A2CCKAROPRM1DRD3 | |
| SCHEMBL22459216 | 0.77 | CTSK (0.48) | DRD4SLC6A2CCKAROPRM1DRD3 | |
| SCHEMBL28451128 | 0.76 | RAB9A (0.49) | LMNASMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL6588494 | 0.76 | NPC1 (0.59) | LMNASMN1; SMN2TSHRNPC1RAB9A | |
| Propham SCHEMBL67344 | 0.76 | SMN1; SMN2 (0.66) | LMNACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| Propham SCHEMBL8536412 | 0.76 | SMN1; SMN2 (0.66) | LMNACYP1A2CYP2D6CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4970217-A | NEUROLEPTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-11-13 | — | — | US | disclosed |