SCHEMBL28451128

SCHEMBL28451128

CCC(Cl)OC(=O)Nc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
KLK7 P49862 2/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 5/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 3/20 0.47
LMNA P02545 2/20 0.47
ATM Q13315 1/20 0.47
HPGD P15428 3/20 0.45
NPC1 O15118 2/20 0.45
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
ALOX15 P16050 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HTT P42858 2/20 0.45
HSP90AA1 P07900 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
HSD17B10 Q99714 2/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10639437 0.81 RAB9A (0.50) RAB9AKLK7MEN1KMT2AMAPT
SCHEMBL7750550 0.80 RAB9A (0.49) RAB9AKLK7MEN1KMT2AMAPT
SCHEMBL11802080 0.79 RAB9A (0.48) RAB9AKLK7MEN1KMT2AALDH1A1
SCHEMBL22459216 0.78 CTSK (0.48) RAB9AKLK7MEN1KMT2AMAPT
SCHEMBL24654619 0.78 KLK7 (0.56) RAB9AKLK7MEN1KMT2AMAPT
Propham SCHEMBL8536412 0.77 SMN1; SMN2 (0.66) RAB9AKLK7MEN1KMT2AMAPT
Propham SCHEMBL67344 0.77 SMN1; SMN2 (0.66) RAB9AKLK7MEN1KMT2AMAPT
SCHEMBL7307219 0.76 CASP3 (0.48) RAB9AKLK7MEN1KMT2AMAPT
SCHEMBL7297799 0.76 CASP3 (0.48) RAB9AKLK7MEN1KMT2AMAPT
SCHEMBL25767097 0.76 RAB9A (0.46) RAB9AKLK7MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111615332-A Compositions, kits and methods for controlling amaranth weeds 维德奥特有限公司 2020-09-01 CN disclosed