Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027681 | 0.89 | ALDH1A1 (0.47) | HRH3DRD3PAOXRAB9ASLC29A1 | |
| SCHEMBL11023279 | 0.86 | CYP2D6 (0.49) | HRH3RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL13265451 | 0.84 | NAAA (0.48) | HRH3DRD3PAOXRAB9ASLC29A1 | |
| SCHEMBL11023682 | 0.84 | CYP2D6 (0.51) | HRH3ALDH1A1KDM4EMEN1CYP2D6 | |
| SCHEMBL562204 | 0.83 | HRH3 (0.47) | HRH3DRD3PAOXRAB9ASLC29A1 | |
| SCHEMBL1301323 | 0.82 | HRH3 (0.49) | HRH3DRD3PAOXRAB9ASLC29A1 | |
| SCHEMBL11024196 | 0.81 | KDM4E (0.50) | HRH3ALDH1A1KDM4EUSP2HPGD | |
| Hydrochloric Acid SCHEMBL1950623 | 0.81 | HRH3 (0.48) | HRH3DRD3PAOXRAB9ASLC29A1 | |
| SCHEMBL16845085 | 0.80 | HRH3 (0.50) | HRH3DRD3PAOXRAB9ASLC29A1 | |
| SCHEMBL11026771 | 0.79 | MEN1 (0.51) | HRH3MEN1CYP2D6MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040793-B1 | NOVEL QUINAZOLINE-DIONE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL USE THEREOF | Ishikawa, Masayuki (JP) | 1985-08-28 | — | — | EP | disclosed |