Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613885 | 0.77 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL21708834 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL15387667 | 0.76 | CYP2D6 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL11755065 | 0.74 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL11757692 | 0.74 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL350877 | 0.74 | CYP2D6 (0.46) | CYP2D6CYP2C19 | |
| SCHEMBL75380 | 0.74 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL7872949 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1LMNA | |
| SCHEMBL32688716 | 0.74 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL710692 | 0.73 | CYP2D6 (0.35) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923943-A | DICYCLOPENTADIENE, NORBORNENYL ESTERS OF NORBORNENYL ACIDS | HERCULES INCORPORATED (US) | 1990-05-08 | — | — | US | disclosed |