Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HINT1 | P49773 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696436 | 0.89 | TYMP (0.36) | TYMP | |
| SCHEMBL10394926 | 0.87 | TYMP (0.51) | PNPTYMPADORA3HPRT1 | |
| SCHEMBL10394454 | 0.82 | TYMP (0.44) | PNPTYMPXDHADORA3MEN1 | |
| SCHEMBL10394453 | 0.82 | TYMP (0.44) | PNPTYMPXDHADORA3MEN1 | |
| SCHEMBL30631035 | 0.73 | TYMP (0.43) | PNPTYMPXDHADORA3MEN1 | |
| SCHEMBL10394333 | 0.72 | TYMP (0.46) | PNPTYMPADORA3 | |
| SCHEMBL7897645 | 0.71 | TYMP (0.50) | PNPTYMPXDHMEN1KMT2A | |
| SCHEMBL16401943 | 0.71 | TYMP (0.49) | TYMPXDHMEN1KMT2ATAAR1 | |
| SCHEMBL10696433 | 0.71 | TYMP (0.41) | TYMPXDHMEN1KMT2A | |
| SCHEMBL7597668 | 0.71 | ADORA3 (0.50) | PNPXDHADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |