Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 7/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.31 |
| ▸ | TNKS | O95271 | 4/20 | 0.31 |
| ▸ | PARP1 | P09874 | 4/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394454 | 0.80 | TYMP (0.44) | SLC6A11SLC6A1TYMPMEN1KMT2A | |
| SCHEMBL10394453 | 0.80 | TYMP (0.44) | SLC6A11SLC6A1TYMPMEN1KMT2A | |
| SCHEMBL10762637 | 0.79 | SLC6A9 (0.34) | SLC6A11SLC6A1TYMPHPRT1TNKS | |
| SCHEMBL10696433 | 0.74 | TYMP (0.41) | SLC6A11SLC6A1TYMPSLC6A12MEN1 | |
| SCHEMBL10394925 | 0.67 | TYMP (0.38) | SLC6A11SLC6A1TYMPSLC6A12MEN1 | |
| SCHEMBL10508847 | 0.64 | TYMS (0.51) | HPRT1 | |
| SCHEMBL30898731 | 0.63 | TYMP (0.51) | TYMP | |
| SCHEMBL30140997 | 0.63 | TYMP (0.51) | TYMP | |
| SCHEMBL9871051 | 0.63 | HPRT1 (0.44) | CYP1A2HPRT1 | |
| SCHEMBL712026 | 0.63 | HPRT1 (0.50) | SLC6A1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |