Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.30 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.30 |
| ▸ | TYMS | P04818 | 2/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394456 | 0.79 | SLC6A11 (0.36) | SLC6A1SLC6A11TYMPTNKSPARP1 | |
| SCHEMBL10394453 | 0.63 | TYMP (0.44) | SLC6A1SLC6A11TYMPHPRT1XDH | |
| SCHEMBL10394454 | 0.63 | TYMP (0.44) | SLC6A1SLC6A11TYMPHPRT1XDH | |
| SCHEMBL10508847 | 0.63 | TYMS (0.51) | HPRT1TYMSXDH | |
| SCHEMBL9020311 | 0.61 | HPRT1 (0.38) | HPRT1 | |
| SCHEMBL6838999 | 0.60 | TYMP (0.59) | TYMPXDH | |
| SCHEMBL6406915 | 0.60 | EDNRA (0.43) | SLC6A1SLC6A11NPY2R | |
| SCHEMBL10759491 | 0.59 | TYMP (0.49) | SLC6A1SLC6A11TYMPXDHBACE1 | |
| SCHEMBL712026 | 0.59 | HPRT1 (0.50) | SLC6A1HPRT1 | |
| SCHEMBL10509246 | 0.58 | MTNR1A (0.47) | HPRT1TYMSXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |