Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | PNP | P00491 | 4/20 | 0.47 |
| ▸ | XDH | P47989 | 5/20 | 0.46 |
| ▸ | TK1 | P04183 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442605 | 0.79 | ADORA3 (0.48) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL1964956 | 0.76 | TK1 (0.46) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL2514560 | 0.75 | TK1 (0.48) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL8490899 | 0.75 | ADORA3 (0.48) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL442295 | 0.75 | ADORA3 (0.48) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL23584333 | 0.75 | ADORA3 (0.46) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL27745728 | 0.75 | ADORA3 (0.48) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL3779345 | 0.75 | ADORA3 (0.46) | ADORA3PNPTK1BLMUSP2 | |
| SCHEMBL9020314 | 0.75 | ADORA3 (0.44) | ADORA3PNPXDHTK1BLM | |
| SCHEMBL7173456 | 0.75 | ADORA3 (0.46) | ADORA3PNPTK1BLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002503673-A | — | — | 2002-02-05 | — | — | JP | claimed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | claimed |