Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150221 | 0.91 | DNM1 (0.32) | DNM1 | |
| SCHEMBL45230 | 0.83 | MAPT (0.42) | MAPTLMNADNM1OPRM1TSHR | |
| SCHEMBL27552948 | 0.83 | MAPT (0.42) | MAPTLMNADNM1OPRM1TSHR | |
| SCHEMBL45436 | 0.80 | MAPT (0.39) | MAPTLMNADNM1OPRM1TSHR | |
| SCHEMBL23825142 | 0.79 | MAPT (0.44) | MAPTLMNACA2FAAHCES1 | |
| SCHEMBL23824979 | 0.79 | MAPT (0.44) | MAPTLMNAFAAHCES1FDPS | |
| SCHEMBL23825196 | 0.79 | MAPT (0.44) | MAPTLMNAFAAHCES1FDPS | |
| SCHEMBL31316959 | 0.79 | MAPT (0.39) | MAPTLMNADNM1OPRM1TSHR | |
| SCHEMBL23825039 | 0.79 | MAPT (0.44) | MAPTLMNACA2FAAHCES1 | |
| SCHEMBL23825006 | 0.79 | MAPT (0.44) | MAPTLMNAFAAHCES1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100254904-A1 | Novel therapeutic delivery systems | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2010-10-07 | — | — | US | claimed |
| US-6479034-B1 | Method of preparing gas and gaseous precursor-filled microspheres | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2002-11-12 | — | — | US | claimed |
| US-20020159952-A1 | Novel acoustically active drug delivery systems | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2002-10-31 | — | — | US | claimed |
| US-6443898-B1 | Therapeutic delivery systems | IMARX PHARMACEUTICAL CORP. | 2002-09-03 | — | — | US | claimed |
| EP-0981333-A4 | NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS | IMARX PHARMACEUTICAL CORP (US) | 2002-04-24 | — | — | EP | claimed |
| US-6071495-A | TEMPERATURE ACTIVATED; PARTICULARLY USEFUL, FOR EXAMPLE, IN ULTRASONIC IMAGING APPLICATIONS AND IN THERAPEUTIC DRUG DELIVERY SYSTEMS. | IMARX PHARMACEUTICAL CORP. (US) | 2000-06-06 | — | — | US | claimed |
| EP-0981333-A1 | NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS | IMARX PHARMACEUTICAL CORP. (US) | 2000-03-01 | — | — | EP | claimed |
| US-5853752-A | Methods of preparing gas and gaseous precursor-filled microspheres | IMARX PHARMACEUTICAL CORP. (US) | 1998-12-29 | — | — | US | claimed |
| WO-1998051284-A1 | NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS | IMARX PHARMACEUTICAL CORP. (US) | 1998-11-19 | — | — | WO | claimed |
| EP-0802788-A4 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER EVAN C (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0712293-A4 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1998-05-06 | — | — | EP | claimed |
| EP-0802788-A1 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER, Evan C (US) | 1997-10-29 | — | — | EP | claimed |
| US-5585112-A | TEMPERATURE-ACTIVATED FLUORINE-CONTAINING GAS; USEFUL IN ULTRASONIC IMAGING AND DRUG DELIVERY SYSTEMS; FDA ORANGE BOOK LISTED PATENT FOR PERFLUTREN | IMARX PHARMACEUTICAL CORP. (US) | 1996-12-17 | — | — | US | claimed |
| EP-0712293-A1 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER, Evan C (US) | 1996-05-22 | — | — | EP | claimed |
| WO-1994028780-A2 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | claimed |
| WO-1994028874-A1 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | claimed |
| EP-2514387-B1 | ULTRASONIC DRUG DELIVERY SYSTEM FOR DENTAL USE | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-9452036-B2 | Dental ultrasonic drug delivery system and dental ultrasonic drug delivery method | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2016-09-27 | — | — | US | disclosed |
| WO-1994028780-A2 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994028874-A1 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020159952-A1 | Novel acoustically active drug delivery systems | AURKA, AURKC, MTDH | MAPT 648/4885LMNA 1467/4885DNM1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.