Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.42 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.42 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 6/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395154 | 0.83 | POLM (0.63) | PIM1POLMPOLKPOLLPOLH | |
| SCHEMBL10395028 | 0.81 | PIM1 (0.50) | PIM1POLMPOLKPOLLPOLH | |
| SCHEMBL10378556 | 0.74 | PIM1 (0.82) | PIM1POLMPOLKPOLLPOLH | |
| SCHEMBL6693604 | 0.73 | ALDH1A1 (0.42) | ALOX15MEN1ALDH1A1TP53MAPT | |
| SCHEMBL8080598 | 0.68 | KDM4E (0.43) | POLMPOLKPOLLPOLHTOP1 | |
| SCHEMBL9006594 | 0.68 | PIM1 (0.49) | PIM1POLMPOLKPOLLPOLH | |
| SCHEMBL10394363 | 0.66 | POLM (0.63) | PIM1POLMPOLKPOLLPOLH | |
| SCHEMBL3054875 | 0.66 | POLM (0.63) | PIM1POLMPOLKPOLLPOLH | |
| SCHEMBL22279459 | 0.65 | KDM4E (0.36) | CYP1A2ALOX15MEN1USP2ALDH1A1 | |
| SCHEMBL22374145 | 0.65 | CES2 (0.33) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900737-A | ANTICANCER AGENTS | GLAXO GROUP LIMITED (GB) | 1990-02-13 | — | — | US | disclosed |