SCHEMBL10396173

SCHEMBL10396173

CC=CC(=O)OCC(O)COc1ccc(C(c2ccc(OCC(O)COC(=O)C=CC)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
POLB P06746 2/20 0.43
LMNA P02545 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CYP1A2 P05177 1/20 0.41
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.38
HIF1A Q16665 1/20 0.38
AR P10275 1/20 0.37
ALDH1A1 P00352 3/20 0.36
PPARD Q03181 1/20 0.36
PLA2G4B P0C869 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59992 0.86 HTT (0.52) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL5664450 0.84 CYP1A2 (0.45) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL941494 0.82 MAPT (0.47) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL1724938 0.81 LMNA (0.41) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL3194813 0.81 LMNA (0.48) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL9177632 0.80 MEN1 (0.49) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL721027 0.80 CYP1A2 (0.48) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL4452659 0.79 POLB (0.47) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL7517507 0.79 POLB (0.46) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL7934548 0.78 MAPT (0.44) MAPTPOLBLMNANPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4910275-A Copolymer of an acrylated polyether and an acrylated ester DAIKIN INDUSTRIES, LTD. (JP) 1990-03-20 US claimed
US-4910275-A Copolymer of an acrylated polyether and an acrylated ester DAIKIN INDUSTRIES, LTD. (JP) 1990-03-20 US disclosed
EP-0305954-A1 Dental material DAIKIN INDUSTRIES, LIMITED (JP) 1989-03-08 EP disclosed