Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.56 |
| ▸ | TUBB | P07437 | 3/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198418 | 0.89 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10396472 | 0.86 | RXRA (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10397857 | 0.86 | PPARG (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10397055 | 0.85 | PPARA (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL107902 | 0.83 | HMGB1 (0.58) | HMGB1CXCL12CFDRXRAALDH1A1 | |
| SCHEMBL6866012 | 0.81 | PPARG (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10395970 | 0.80 | TUBB1 (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10397460 | 0.79 | PPARG (0.56) | PPARGPPARALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL9558573 | 0.78 | PPARG (0.57) | PPARGPPARALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL10396478 | 0.78 | L3MBTL1 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |