Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517486 | 0.93 | SIGMAR1 (0.68) | SIGMAR1HTR1AKDM4EMEN1KMT2A | |
| SCHEMBL17792374 | 0.88 | SIGMAR1 (0.60) | SIGMAR1HTR1AKDM4EMEN1KMT2A | |
| SCHEMBL16335361 | 0.85 | SIGMAR1 (0.75) | SIGMAR1HTR1AGRIN2B | |
| SCHEMBL22528263 | 0.85 | SIGMAR1 (0.79) | SIGMAR1HTR1AGRIN2B | |
| SCHEMBL28435581 | 0.84 | PRMT5 (0.58) | SIGMAR1HTR1AKDM4EMEN1KMT2A | |
| SCHEMBL16335245 | 0.84 | SIGMAR1 (0.73) | SIGMAR1HTR1AGRIN2B | |
| SCHEMBL6369610 | 0.81 | HTR1A (0.71) | SIGMAR1HTR1AKDM4EMEN1KMT2A | |
| SCHEMBL1415530 | 0.79 | HTR1A (0.81) | SIGMAR1HTR1AKDM4EMEN1KMT2A | |
| SCHEMBL967323 | 0.78 | ALDH1A1 (0.71) | SIGMAR1HTR1AKDM4EMEN1KMT2A | |
| SCHEMBL14656766 | 0.78 | SIGMAR1 (0.61) | SIGMAR1HTR1AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977159-A | HYPOTENSIVE AGENTS | SYNTHELABO (FR) | 1990-12-11 | — | — | US | disclosed |