Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443405 | 1.00 | SIGMAR1 (0.61) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL17517486 | 0.84 | SIGMAR1 (0.68) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL6369610 | 0.81 | HTR1A (0.71) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL1415530 | 0.79 | HTR1A (0.81) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL10397222 | 0.78 | SIGMAR1 (0.61) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL10675764 | 0.77 | SIGMAR1 (0.74) | SIGMAR1HTR1AGRIN2B | |
| SCHEMBL22549325 | 0.77 | HTR1A (0.62) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL22528263 | 0.77 | SIGMAR1 (0.79) | SIGMAR1HTR1AGRIN2B | |
| SCHEMBL967638 | 0.77 | HDAC1 (0.60) | SIGMAR1HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL17792374 | 0.77 | SIGMAR1 (0.60) | SIGMAR1HTR1AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270750-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-08-31 | — | — | US | disclosed |
| EP-4188919-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | Etat Français représenté par la Direction Centrale Du Service de Santé des Armées (FR) | 2023-06-07 | — | — | EP | disclosed |
| US-9290750-B2 | 7,11-methanocycloocta [b] quinoline derivative as highly functionalizable acetylcholinesterase inhibitors | UNIVERSITE DE ROUEN (FR) | 2016-03-22 | — | — | US | disclosed |
| US-20150197735-A1 | 7,11-METHANOCYCLOOCTA [B] QUINOLINE DERIVATIVE AS HIGHLY FUNCTIONALIZABLE ACETYLCHOLINESTERASE INHIBITORS | UNIVERSITE DE ROUEN (FR) | 2015-07-16 | — | — | US | disclosed |
| US-9040506-B2 | 7,11-methanocycloocta [B] quinoline derivative as highly functionalizable acetylcholinesterase inhibitors | UNIVERSITE DE ROUEN (FR) | 2015-05-26 | — | — | US | disclosed |
| EP-2556057-B1 | 7,11-METHANOCYCLOOCTA[B]QUINOLINE DERIVATIVE AS HIGHLY FUNCTIONALIZABLE ACETYLCHOLINESTERASE INHIBITORS | UNIV ROUEN (FR) | 2014-08-27 | — | — | EP | disclosed |
| US-20130029941-A1 | 7,11-METHANOCYCLOOCTA [B] QUINOLINE DERIVATIVE AS HIGHLY FUNCTIONALIZABLE ACETYLCHOLINESTERASE INHIBITORS | UNIVERSITE DE ROUEN (FR) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029941-A1 | 7,11-METHANOCYCLOOCTA [B] QUINOLINE DERIVATIVE AS HIGHLY FUNCTIONALIZABLE ACETYLCHOLINESTERASE INHIBITORS | ACHE, BCHE, CHRNA7 | SIGMAR1 2461/4885HTR1A 245/4885MEN1 1574/4885 |
| US-20230270750-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | BCHE, ACHE, CHAT | SIGMAR1 2311/4885HTR1A 2783/4885MEN1 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.