Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | COASY | Q13057 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245583 | 0.90 | PDE10A (0.54) | PDE10AGRIN1GRIN2BPOLB | |
| SCHEMBL10072578 | 0.86 | GRIN1 (0.54) | PDE10AGRIN1GRIN2BCHEK1MGAM | |
| SCHEMBL15767180 | 0.82 | CHEK1 (0.41) | PDE10ACHEK1DDAH1POLBKDM4E | |
| SCHEMBL1917210 | 0.81 | MGAM (0.47) | MGAMGAASIMGAM2 | |
| SCHEMBL9533100 | 0.81 | GRIN1 (0.55) | PDE10AGRIN1GRIN2BCHEK1MGAM | |
| SCHEMBL9754832 | 0.80 | ALDH1A1 (0.46) | PDE10ACHEK1DDAH1POLBKDM4E | |
| SCHEMBL1917492 | 0.80 | PSMB8 (0.49) | CHEK1MGAMGAASIMGAM2 | |
| SCHEMBL7964155 | 0.80 | CHEK1 (0.58) | PDE10ACHEK1GAADDAH1POLB | |
| SCHEMBL4066021 | 0.79 | GRIN1 (0.54) | PDE10AGRIN1GRIN2BCHEK1MGAM | |
| SCHEMBL4761212 | 0.78 | PARP1 (0.61) | PDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929534-A | DEVELOPER RESISTANCE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |
| EP-0305873-A2 | Positive photosensitive composition and photosensitive registration material made therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |