SCHEMBL3245583

SCHEMBL3245583

CCCCc1nc2c(O)cccc2[nH]1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.54
GRIN1 Q05586 1/20 0.49
GRIN2B Q13224 1/20 0.49
POLB P06746 1/20 0.44
PARP1 P09874 1/20 0.42
GPR84 Q9NQS5 2/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397230 0.90 PDE10A (0.57) PDE10AGRIN1GRIN2BPOLB
SCHEMBL10072578 0.83 GRIN1 (0.54) PDE10AGRIN1GRIN2BPARP1ALDH1A1
SCHEMBL6755252 0.83 MGAM (0.45) POLBALDH1A1
SCHEMBL28871299 0.81 POLB (0.44) POLBPARP1ALDH1A1
SCHEMBL6653125 0.81 GPR84 (0.41) PARP1GPR84ALDH1A1
SCHEMBL29968130 0.81 POLB (0.44) POLBPARP1ALDH1A1
SCHEMBL9756381 0.80 KDM4E (0.51) PARP1
SCHEMBL5335148 0.79 HRH3 (0.45) PDE10APARP1
SCHEMBL9533100 0.78 GRIN1 (0.55) PDE10AGRIN1GRIN2BALDH1A1
SCHEMBL6753968 0.78 POLB (0.47) POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002520-B1 Composition for oxidative dying of keratinous fibres and dying process therewith OREAL (FR) 2008-10-29 EP claimed
EP-0988021-B1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME OREAL (FR) 2003-11-12 EP claimed
EP-1181005-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-02-27 EP claimed
WO-2001066071-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
EP-1047381-A1 KERATINOUS FIBRE OXIDATION DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME L'OREAL (FR) 2000-11-02 EP claimed
EP-0728466-B1 Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process OREAL (FR) 2000-06-14 EP claimed
EP-1002520-A1 Composition for oxidative dying of keratinous fibres and dying process therewith L'OREAL (FR) 2000-05-24 EP claimed
EP-0988021-A1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME L'OREAL (FR) 2000-03-29 EP claimed
WO-1999036039-A1 KERATINOUS FIBRE OXIDATION DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME L'OREAL (FR) 1999-07-22 WO claimed
WO-1998055083-A1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME L'OREAL (FR) 1998-12-10 WO claimed
EP-0728464-B1 Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process OREAL (FR) 1997-07-30 EP claimed
EP-0605320-B1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same OREAL (FR) 1997-04-09 EP claimed
EP-0728466-A1 Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process L'OREAL (FR) 1996-08-28 EP claimed
EP-0728464-A1 Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process L'OREAL (FR) 1996-08-28 EP claimed
EP-0605320-A1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same L'OREAL (FR) 1994-07-06 EP claimed
EP-1200052-B1 DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP OREAL (FR) 2010-05-26 EP disclosed
EP-1002520-B1 Composition for oxidative dying of keratinous fibres and dying process therewith OREAL (FR) 2008-10-29 EP disclosed
EP-0728464-A1 Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process L'OREAL (FR) 1996-08-28 EP disclosed
EP-0728466-A1 Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process L'OREAL (FR) 1996-08-28 EP disclosed
EP-0605320-A1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same L'OREAL (FR) 1994-07-06 EP disclosed