Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024329 | 0.81 | MAPT (0.36) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL11802753 | 0.76 | CA1 (0.45) | MAPTNPC1HTTCRHR1RAB9A | |
| SCHEMBL8024333 | 0.76 | KMT2A (0.40) | MAPTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10397259 | 0.74 | MAPT (0.50) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27614713 | 0.74 | PMM2 (0.46) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9258251 | 0.74 | GPR35 (0.50) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL10397256 | 0.73 | CA1 (0.43) | MAPTCRHR1CYP3A4ALOX5TSHR | |
| SCHEMBL28220369 | 0.72 | GPR35 (0.47) | MAPTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL28233524 | 0.71 | GRIN2D (0.41) | MAPTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6129304 | 0.71 | MEN1 (0.44) | MAPTNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960435-A | HEAT TREATING IN AQUEOUS SOLVENT OR ANIONIC OR NONIONIC SURFACTANT; COLORFAST | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-10-02 | — | — | US | disclosed |