Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048383 | 0.78 | MEN1 (0.48) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL10397258 | 0.74 | MAPT (0.42) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL13219022 | 0.73 | MAPT (0.59) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL30620152 | 0.73 | MAPT (0.63) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL28287460 | 0.72 | MAPT (0.66) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL27973104 | 0.72 | MAPT (0.66) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL11883065 | 0.72 | TDP1 (0.51) | MAPTHTTSMN1; SMN2CYP19A1KMT2A | |
| SCHEMBL10442506 | 0.71 | MAPT (0.41) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL11694170 | 0.71 | MAPT (0.49) | MAPTHTTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL11694161 | 0.71 | MAPT (0.49) | MAPTHTTNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960435-A | HEAT TREATING IN AQUEOUS SOLVENT OR ANIONIC OR NONIONIC SURFACTANT; COLORFAST | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-10-02 | — | — | US | disclosed |