Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397258 | 0.81 | MAPT (0.42) | MAPTL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL8024333 | 0.77 | KMT2A (0.40) | MAPTTDP1RAB9ANPC1MEN1 | |
| SCHEMBL125385 | 0.75 | ALDH1A1 (0.56) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL9258251 | 0.75 | GPR35 (0.50) | MAPTMAPK1TDP1L3MBTL1NPSR1 | |
| SCHEMBL18037665 | 0.75 | GPR35 (0.50) | MAPTMAPK1TDP1L3MBTL1NPSR1 | |
| SCHEMBL28220369 | 0.73 | GPR35 (0.47) | MAPTTDP1RAB9ANPC1MEN1 | |
| SCHEMBL8024323 | 0.72 | MAPT (0.35) | MAPTMAPK1TDP1L3MBTL1NPSR1 | |
| SCHEMBL28233524 | 0.72 | GRIN2D (0.41) | MAPTMAPK1TDP1L3MBTL1NPSR1 | |
| SCHEMBL27614713 | 0.72 | PMM2 (0.46) | MAPTMAPK1TDP1L3MBTL1NPSR1 | |
| SCHEMBL6129304 | 0.72 | MEN1 (0.44) | MAPTMAPK1TDP1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000054103-A1 | CHIRAL POLYMER COMPOSITIONS EXHIBITING NONLINEAR OPTICAL PROPERTIES | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 2000-09-14 | — | — | WO | disclosed |