Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.72 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.72 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.59 |
| ▸ | HNF4A | P41235 | 2/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | SGK1 | O00141 | 1/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ACLY | P53396 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770912 | 0.92 | DCLRE1B (0.59) | DCLRE1BDCLRE1AACMSDHNF4AHSD17B1 | |
| SCHEMBL7019419 | 0.88 | DCLRE1B (0.66) | DCLRE1BDCLRE1AACMSDHNF4AHSD17B1 | |
| SCHEMBL9518777 | 0.86 | DCLRE1B (0.55) | DCLRE1BDCLRE1AACMSDHNF4AHSD17B1 | |
| SCHEMBL13681701 | 0.84 | DCLRE1B (0.66) | DCLRE1BDCLRE1AACMSDHNF4ASGK1 | |
| SCHEMBL11296003 | 0.84 | DCLRE1B (0.70) | DCLRE1BDCLRE1AACMSDHNF4ADHFR | |
| SCHEMBL10463853 | 0.83 | DCLRE1B (0.51) | DCLRE1BDCLRE1AHSD17B1SGK1CAMKK2 | |
| SCHEMBL28373110 | 0.82 | FOLH1 (0.55) | DCLRE1BDCLRE1AACMSDHNF4ADHFR | |
| Hydrochloric Acid SCHEMBL5704000 | 0.82 | DCLRE1B (0.62) | DCLRE1BDCLRE1AACMSDHNF4ASGK1 | |
| SCHEMBL28369703 | 0.81 | CLCN2 (0.54) | DCLRE1BDCLRE1AACMSDHNF4ADHFR | |
| SCHEMBL12166068 | 0.80 | SGK1 (0.50) | DCLRE1BDCLRE1AACMSDHSD17B1SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |