SCHEMBL2770912

SCHEMBL2770912

CCc1cc(-c2ccc(C(=O)O)c(CC)c2)ccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCLRE1B Q9H816 3/20 0.59
HSD17B1 P14061 2/20 0.59
DCLRE1A Q6PJP8 1/20 0.59
SGK1 O00141 1/20 0.48
CAMKK2 Q96RR4 1/20 0.48
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47
GABRG3 Q99928 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397478 0.92 DCLRE1B (0.72) DCLRE1BHSD17B1DCLRE1ASGK1CAMKK2
SCHEMBL9518777 0.89 DCLRE1B (0.55) DCLRE1BHSD17B1DCLRE1ASGK1CAMKK2
SCHEMBL10463853 0.86 DCLRE1B (0.51) DCLRE1BHSD17B1DCLRE1ASGK1CAMKK2
SCHEMBL277909 0.83 ALDH1A1 (0.54) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2771168 0.83 KDM4E (0.52) DCLRE1BHSD17B1DCLRE1AGABRPGABRD
SCHEMBL21625826 0.82 SGK1 (0.49) DCLRE1BHSD17B1DCLRE1ASGK1CAMKK2
SCHEMBL3385017 0.81 ALDH1A1 (0.52) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL39010 0.81 CA12 (0.57) HSD17B1CAMKK2GABRPGABRDGABRA1
SCHEMBL28126806 0.81 CA12 (0.57) HSD17B1CAMKK2GABRPGABRDGABRA1
SCHEMBL1549076 0.81 CSNK2A1 (0.53) DCLRE1BHSD17B1DCLRE1AGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100323217-A1 MATERIAL FOR AN ELECTRICAL/ELECTRONIC PART AND ELECTRICAL/ELECTRONIC PART THE FURUKAWA ELECTRIC CO., LTD. (JP) 2010-12-23 US disclosed
EP-2248663-A1 MATERIAL FOR ELECTRICAL/ELECTRONIC COMPONENT AND ELECTRICAL/ELECTRONIC COMPONENT The Furukawa Electric Co., Ltd. (JP) 2010-11-10 EP disclosed
EP-0977209-B1 INSULATED WIRE FURUKAWA ELECTRIC CO LTD (JP) 2006-07-12 EP disclosed
US-6436537-B1 INSULATED WIRES WITH POLYAMIDEIMIDE COPOLYMERS THE FURUKAWA ELECTRIC CO., LTD. (JP) 2002-08-20 US disclosed
EP-0977209-A1 INSULATED WIRE THE FURUKAWA ELECTRIC CO., LTD. (JP) 2000-02-02 EP disclosed