Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.54 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | BAD | Q92934 | 2/20 | 0.48 |
| ▸ | SGK1 | O00141 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770912 | 0.89 | DCLRE1B (0.59) | DCLRE1BHSD17B1DCLRE1ARARBRARA | |
| SCHEMBL10397478 | 0.86 | DCLRE1B (0.72) | DCLRE1BHSD17B1DCLRE1ASGK1CAMKK2 | |
| SCHEMBL65008 | 0.85 | KEAP1 (0.50) | DCLRE1BRARBRARARARGSGK1 | |
| Hydrochloric Acid SCHEMBL29118324 | 0.84 | KEAP1 (0.48) | DCLRE1BRARBRARARARGSGK1 | |
| SCHEMBL10463853 | 0.80 | DCLRE1B (0.51) | DCLRE1BHSD17B1DCLRE1ASGK1CAMKK2 | |
| SCHEMBL14252284 | 0.80 | BCL2L1 (0.57) | DCLRE1BDCLRE1ARARBRARARARG | |
| SCHEMBL14089891 | 0.79 | RXRB (0.61) | DCLRE1BHSD17B1RARBRARARARG | |
| SCHEMBL18069872 | 0.79 | MAPT (0.49) | HSD17B1KDM4ELMNAHSD17B10MEN1 | |
| SCHEMBL2250853 | 0.79 | DCLRE1B (0.54) | DCLRE1BDCLRE1ARARBRARARARG | |
| SCHEMBL2251799 | 0.79 | DCLRE1B (0.57) | DCLRE1BDCLRE1ARARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490962-A4 | ANTIPSYCHOTIC 1-CYCLOALKYLPIPERIDINES | — | 1993-03-03 | — | — | EP | disclosed |